Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.

Title:

Dataset

identifier:	1650256
description:	epitope description:KRGFGFVTFDDHDPVDKIVLQ antigen name:Heterogeneous nuclear ribonucleoproteins A2/B1 host organism:Mus musculus hTNF Tg
aggregation:	instance of dataset
availability:	available
primaryPublications:	16339574

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1015135
landingPage:	http://www.iedb.org/assay/1650256

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2005

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	Silvia Hayer Makiyeh Tohidast-Akrad Silva Haralambous Beatrice Jahn-Schmid Karl Skriner Sylvie Trembleau Hé lè ne Dumortier Serafin Pinol-Roma Kurt Redlich Georg Schett Sylviane Muller George Kollias Josef Smolen Gü nter Steiner

Data Type

method:	western blot

Study

name:	Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.
description:	The epitope sequence is from the reference cited: Dumortier et al. (2000) J Immunol 165: 2297-2305 [PMID: 10925319]. Sera from 2 of 5 hTNF Tg mice immunized with the epitope reacted with HeLa nuclear proteins by Western blotting.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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