Opposite effects of immunotherapy with ovalbumin and the immunodominant T-cell epitope on airway eosinophilia and hyperresponsiveness in a murine model of allergic asthma.

Title:

Opposite effects of immunotherapy with ovalbumin and the immunodominant T-cell epitope on airway eosinophilia and hyperresponsiveness in a murine model of allergic asthma.

Dataset

identifier:	1645676
description:	epitope description:ISQAVHAAHAEINEAGR antigen name:Gal d 2 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	10385589

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014021
landingPage:	http://www.iedb.org/assay/1645676

Publication

type:	Literature
publicationVenue:	Am J Respir Cell Mol Biol
dates:	1999

Dimension

study type:	b cell assays
subject species:	Gallus gallus

Person

fullName:	E M Janssen M H Wauben E H Jonker G Hofman W Van Eden F P Nijkamp A J Van Oosterhout

Data Type

method:	antigen inhibition

Study

name:	Opposite effects of immunotherapy with ovalbumin and the immunodominant T-cell epitope on airway eosinophilia and hyperresponsiveness in a murine model of allergic asthma.
description:	The epitope sequence is derived from Shimonkevitz et al., J Immunol 133 (4): 2067 (1984) [PMID: 6332146]. OVA-sensitized and -challenged animals had epitope specific IgG1 as shown by the epitope inhibition of IgG1 binding to OVA-coated ELISA plates.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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