Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.

Title:

Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.

Dataset

identifier:	1646082
description:	epitope description:DAEFRHDSGYE antigen name:Amyloid beta A4 protein host organism:Mus musculus APPsw
aggregation:	instance of dataset
availability:	available
primaryPublications:	17545160

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1009903
landingPage:	http://www.iedb.org/assay/1646082

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2007

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Grigor Mamikonyan Mihaela Necula Mikayel Mkrtichyan Anahit Ghochikyan Irina Petrushina Nina Movsesyan Erene Mina Anatoly Kiyatkin Charles G Glabe David H Cribbs Michael G Agadjanyan

Data Type

method:	immuno staining

Study

name:	Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.
description:	Antibody to the epitope bound to amyloid plaques from human brain with Alzheimer's disease, and to APP mouse brain in a Western blot

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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