Immunological Data Discovery Index
Advanced Search
identifier: 1646808
description:
epitope description:YKVIHAWLI
antigen name:Presenilin-1
host organism:Mus musculus BALB/c
antibody name:C8A5, D3G6
aggregation:
instance of dataset
availability:
available
primaryPublications: 9200512
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1008822
landingPage: http://www.iedb.org/assay/1646808
type:
Literature
publicationVenue:
Brain Res
dates:
1997
study type: b cell assays
subject species: Homo sapiens
fullName:
K S Kim
J Wegiel
V Sapienza
J Chen
H Hong
H M Wisniewski
method:
immuno staining
name:
Immunoreactivity of presenilin-1 in human, rat and mouse brain.
description:
The epitope-specific mAbs immunolabeled intracytoplasmic material in neurons in the cerebral and cerebellar cortex, as well as gray matter in the brains of AD subjects, individuals with Down syndrome, and normal subjects. Granular immunopositive material was found in neuronal perikarya, dendrites, and axons in cortical, hippocampal, and basal ganglia neurons in brain as well as in Purkinje cells in cerebellum.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.