Potential preventive effects of follistatin-related protein/TSC-36 on joint destruction and antagonistic modulation of its autoantibodies in rheumatoid arthritis.

Title:

Potential preventive effects of follistatin-related protein/TSC-36 on joint destruction and antagonistic modulation of its autoantibodies in rheumatoid arthritis.

Dataset

identifier:	1646816
description:	epitope description:LKFVEQNE antigen name:Follistatin-related protein 1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	12502727

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014565
landingPage:	http://www.iedb.org/assay/1646816

Publication

type:	Literature
publicationVenue:	Int Immunol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Masao Tanaka Shoichi Ozaki Daisuke Kawabata Masaaki Kishimura Fumio Osakada Mitsuo Okubo Masao Murakami Kazuwa Nakao Tsuneyo Mimori

Data Type

method:	biological activity

Study

name:	Potential preventive effects of follistatin-related protein/TSC-36 on joint destruction and antagonistic modulation of its autoantibodies in rheumatoid arthritis.
description:	Epitope-specific auto-antibodies from RA patients were shown to increase the production of destructive mediators (MMP-1, MMP-3 and PGE2) in synovial fluid by blocking (inhibiting) FRP.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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