| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1014714 |
| landingPage: |
http://www.iedb.org/assay/1647126 |
| type: |
Literature
|
| publicationVenue: |
J Am Soc Nephrol
|
| dates: |
2006
|
| study type: | b cell assays |
| subject species: | Rattus norvegicus |
| fullName: |
Lanlin Chen
Thomas Hellmark
Vadim Pedchenko
Billy G Hudson
Charles D Pusey
Jay W Fox
W Kline Bolton
|
| method: |
ELISA
|
| name: |
A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.
|
| description: |
A significant increase in serum antibody to alpha3(IV)NC1 and alpha4(IV)NC1 domains was evident by 4 weeks after immunization with the epitope. Antibodies that were eluted from human kidneys of nephritic rats also bound to human 3(IV)NC1in ELISA or Western blot, and in addition stained rat kidney sections in indirect immunofluorescence.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |