Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies.

Title:

Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies.

Dataset

identifier:	1647157
description:	epitope description:RSFTLASSETG antigen name:Chitinase-3-like protein 1 host organism:Mus musculus BALB/c antibody name:mAb 12A
aggregation:	instance of dataset
availability:	available
primaryPublications:	12759455

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014550
landingPage:	http://www.iedb.org/assay/1647157

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Peter G A Steenbakkers Dominique Baeten Eric Rovers Eric M Veys Antonius W M Rijnders Jan Meijerink Filip De Keyser Annemieke M H Boots

Data Type

method:	immuno staining

Study

name:	Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies.
description:	Epitope-specific mAbs were able to detect DRB10401 and HC-39 (263-275) complexes in the synovial fluid of 5 out of 8 RA patients. No staining with mAb 12A was observed in eight DRB10401-negative RA patients, and no staining was observed in 8 spondyloarthropathy and osteoarthritis controls.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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