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Title: Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.
identifier: 1648281
description:
epitope description:KETELLYEYHDTGTAIISKN
antigen name:Erythrocyte membrane protein 1, PfEMP1 (UniProt:Q8I639)
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 17112315
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014481
landingPage: http://www.iedb.org/assay/1648281
type:
Literature
publicationVenue:
PLoS Pathog
dates:
2006
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
Madeleine Dahlbä
ck
Thomas S Rask
Pernille H Andersen
Morten A Nielsen
Nicaise T Ndam
Mafalda Resende
Louise Turner
Philippe Deloron
Lars Hviid
Ole Lund
Anders Gorm Pedersen
Thor G Theander
Ali Salanti
method:
ELISA
name:
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.
description:
The epitope was deduced.
The pools of sera were deduced to react specifically to this region by pepscan analysis of overlapping peptides after affinity purification of the sera with purified DBL3X domain of VAR2CSA (for Ghanaian women) or preincubation of the serum with P.falciparum infected erythrocytes (for Tanzanian women).

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