Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions.

Title:

Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions.

Dataset

identifier:	1648352
description:	epitope description:HCLGKWLGHPDKF antigen name:Myelin proteolipid protein host organism:Mus musculus SJL antibody name:J1-03
aggregation:	instance of dataset
availability:	available
primaryPublications:	11525809

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014832
landingPage:	http://www.iedb.org/assay/1648352

Publication

type:	Literature
publicationVenue:	J Neuroimmunol
dates:	2001

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	J D Laman L Visser C B Maassen C J de Groot L A de Jong B A 't Hart M van Meurs M M Schellekens

Data Type

method:	immuno staining

Study

name:	Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions.
description:	The epitope-specific mAb bound to active demyelinating lesion in a human multiple sclerosis brain section.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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