X-ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease.

Title:

X-ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease.

identifier:	1648933
description:	epitope description:TDHGAE antigen name:Other Homo sapiens (human) protein host organism:Mus musculus C3H antibody name:MN423
aggregation:	instance of dataset
availability:	available
primaryPublications:	18061582

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Jozef Sevcik Rostislav Skrabana Radovan Dvorsky Natalia Csokova Khalid Iqbal Michal Novak

method:	surface plasmon resonance (SPR)

name:	X-ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease.
description:	The epitope is a peptide from the C-terminal of paired helical filaments (PHF) core, protease resistant product of proteolytic cleavage of Alzheimer's PHF and consists mainly of tau protein. The epitope-specific mAb bound to core tau paired helical fragments with two-phase kinetics.

name:	iedb
homePage:	http://www.iedb.org

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