Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.

Title:

Dataset

identifier:	1651293
description:	epitope description:LCRQHMATKSLFNRAEGPPEP antigen name:Receptor-type tyrosine-protein phosphatase-like N host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	11937581

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007510
landingPage:	http://www.iedb.org/assay/1651293

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2002

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Massimo Bearzatto Heike Naserke Sandra Piquer Kerstin Koczwara Vito Lampasona Alistair Williams Michael R Christie Polly J Bingley Anette-G Ziegler Ezio Bonifacio

Data Type

method:	antigen inhibition

Study

name:	Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.
description:	Pre-incubation with the epitope with sera did not inhibit binding of sera to the I-2601-682/IA-2beta737-1033 chimeric protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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