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identifier: 1651538
description:
epitope description:WQEGNVF
antigen name:Immunoglobulin
host organism:Homo sapiens
antibody name:RF McC and Clau
aggregation:
instance of dataset
availability:
available
primaryPublications: 7532785
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1015812
landingPage: http://www.iedb.org/assay/1651538
type:
Literature
publicationVenue:
Mol Immunol
dates:
1995
study type: b cell assays
subject species: Homo sapiens
fullName:
C Peterson
C C Malone
R C Williams Jr
method:
antigen inhibition
name:
Rheumatoid-factor-reactive sites on CH3 established by overlapping 7-mer peptide epitope analysis.
description:
Epitope inhibited binding of polyclonal RFs to whole human IgG. Binding was also seen in direct ELISA. Substitution analysis revealed that the most important residues for binding are G3 and F7, and to a much lesser extent, W1, G2, N5, and V6.

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