Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20 -- 38) peptide displayed on bacterial thioredoxin.

Title:

Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20 -- 38) peptide displayed on bacterial thioredoxin.

identifier:	1654581
description:	epitope description:GPVGPSDPSIVSLVEETSFI antigen name:Minor capsid protein L2 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	19368776

study type:	b cell assays
subject species:	Human papillomavirus type 16

fullName:	Ivonne Rubio Angelo Bolchi Nadia Moretto Elena Canali Lutz Gissmann Massimo Tommasino Martin Mü ller Simone Ottonello

method:	ELISA

name:	Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20 -- 38) peptide displayed on bacterial thioredoxin.
description:	The epitope sequence was cited in Pastrana et al. (2005) Virology. 2005 Jul 5 337(2):365-72 [PMID: 15885736]. The epitope-specific antiserum raised against the TRX conjugated epitope recognized the antigen, but the antiserum raised against KLH-conjugated epitope did not. Immunization of mice with multimers (4-, or 8-mer) of the epitope conjugated to TRX lead to a higher epitope-specific titer.

name:	iedb
homePage:	http://www.iedb.org

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