Detection of antibodies against a human papillomavirus (HPV) type 16 peptide that differentiate high-risk from low-risk HPV-associated low-grade squamous intraepithelial lesions.

Title:

Detection of antibodies against a human papillomavirus (HPV) type 16 peptide that differentiate high-risk from low-risk HPV-associated low-grade squamous intraepithelial lesions.

Dataset

identifier:	1655089
description:	epitope description:IHSMNSTIL antigen name:Major capsid protein L1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15302958

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1015798
landingPage:	http://www.iedb.org/assay/1655089

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	2004

Dimension

study type:	b cell assays
subject species:	Human papillomavirus type 16

Person

fullName:	Leticia Rocha-Zavaleta Juana P Ambrosio Maria de Lourdes Mora-Garcia Fernando Cruz-Talonia Jorge Hernandez-Montes Benny Weiss-Steider Vianney Ortiz-Navarrete Alberto Monroy-Garcia

Data Type

method:	ELISA

Study

name:	Detection of antibodies against a human papillomavirus (HPV) type 16 peptide that differentiate high-risk from low-risk HPV-associated low-grade squamous intraepithelial lesions.
description:	Similar results were observed for IgA antibody responses in cervical secretions. Seropositivity in cervical cancer patients was significantly lower than that detected in high-risk HPV-associated LSIL patients. The 16L1 peptide-based ELISA was able to detect a high proportion (91.6%) of LSIL patients who were actually infected with high-risk HPV types and produced low levels of false-positive and false-negative results.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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