Identification of two independent neutralization domains on the VP4 trypsin cleavage products VP5* and VP8* of human rotavirus ST3.

Title:

Identification of two independent neutralization domains on the VP4 trypsin cleavage products VP5* and VP8* of human rotavirus ST3.

identifier:	1658369
description:	epitope description:E217 antigen name:Outer capsid protein VP4 host organism:Mus musculus BALB/c antibody name:HS11
aggregation:	instance of dataset
availability:	available
primaryPublications:	7530390

study type:	b cell assays
subject species:	Human rotavirus G4 strain St. Thomas 3

fullName:	L Padilla-Noriega S J Dunn S Ló pez H B Greenberg C F Arias

method:	biological activity

name:	Identification of two independent neutralization domains on the VP4 trypsin cleavage products VP5* and VP8* of human rotavirus ST3.
description:	The mAb HS11 neutralized Human rotavirus ST3 but not escape variants. Gene 4 (VP4) sequencing of an escape variant revealed an amino acid substitution in E217.

name:	iedb
homePage:	http://www.iedb.org

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