Serum antibody responses against human papillomavirus in relation to tumor characteristics, response to treatment, and survival in carcinoma of the uterine cervix.

Title:

Serum antibody responses against human papillomavirus in relation to tumor characteristics, response to treatment, and survival in carcinoma of the uterine cervix.

Dataset

identifier:	1657106
description:	epitope description:HKSAIVTLTYDSEWQRDQ antigen name:Regulatory protein E2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7728779

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006507
landingPage:	http://www.iedb.org/assay/1657106

Publication

type:	Literature
publicationVenue:	Cancer Immunol Immunother
dates:	1995

Dimension

study type:	b cell assays
subject species:	Human papillomavirus type 16

Person

fullName:	P Lenner J Dillner F Wiklund G Hallmans U Stendahl

Data Type

method:	ELISA

Study

name:	Serum antibody responses against human papillomavirus in relation to tumor characteristics, response to treatment, and survival in carcinoma of the uterine cervix.
description:	Epitope sequence is found in reference Dillner et al., Cancer Res. 1994 Jan 1 54(1):134-41, [PMID: 8261434]. An extra cysteine was added to the C-terminus during peptide synthesis. An increased pretreatment antibody level was found to be associated with a shortened survival for IgA responses against the epitope. In patients who received cancer treatment and showed complete remission, a significant decline of epitope-specific Ab levels was found.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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