Diagnostic phase antibody response to the human papillomavirus type 16 E2 protein is associated with successful treatment of genital HPV lesions with systemic interferon alpha-2b.

Title:

Diagnostic phase antibody response to the human papillomavirus type 16 E2 protein is associated with successful treatment of genital HPV lesions with systemic interferon alpha-2b.

Dataset

identifier:	1657282
description:	epitope description:HKSAIVTLTYDSEWQRDQ antigen name:Regulatory protein E2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9126686

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006502
landingPage:	http://www.iedb.org/assay/1657282

Publication

type:	Literature
publicationVenue:	Clin Diagn Virol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Human papillomavirus type 16

Person

fullName:	G Stellato J Paavonen P Nieminen M Hibma P Vilja M Lehtinen

Data Type

method:	ELISA

Study

name:	Diagnostic phase antibody response to the human papillomavirus type 16 E2 protein is associated with successful treatment of genital HPV lesions with systemic interferon alpha-2b.
description:	HPV antibody status was available from 81 cases. Among 43 patients received IFN-alpha treatment, 11 showed reactivity to the epitope. Among 45 patients received the placebo, 12 showed reactivity to the epitope. Overall, adjuvant therapy with systemic IFN-alpha did not differ from placebo.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.