| identifier: | 1657371 |
| description: |
epitope description:YDDVENSGGYGGNPGQDNRV
antigen name:Major capsid protein L1 (UniProt:P04012)
host organism:Mus musculus BALB/c
antibody name:H11.A3.2, H11.B2, H11.F1, H11.G5, H11.H3
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
9094659 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1015877 |
| landingPage: |
http://www.iedb.org/assay/1657371 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
1997
|
| study type: | b cell assays |
| subject species: | Human papillomavirus type 11 |
| fullName: |
S W Ludmerer
D Benincasa
G E Mark 3rd
N D Christensen
|
| method: |
ELISA
|
| name: |
A neutralizing epitope of human papillomavirus type 11 is principally described by a continuous set of residues which overlap a distinct linear, surface-exposed epitope.
|
| description: |
The epitope-specific mAbs recognized HPV11 virus-like particles. Single substitution at positions 1, 8, 9, 16, and 20 resulted in a great loss of antibody, indicating these residues as critical for binding. Substitutions into the HPV16 E11 sequence conferred HPV11 mAb binding and demonstrated a continuous, conformational epitope.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |