Mapping of IgE-binding epitopes on the major latex allergen Hev b 2 and the cross-reacting 1,3beta-glucanase fruit allergens as a molecular basis for the latex-fruit syndrome.

Title:

Mapping of IgE-binding epitopes on the major latex allergen Hev b 2 and the cross-reacting 1,3beta-glucanase fruit allergens as a molecular basis for the latex-fruit syndrome.

Dataset

identifier:	1657772
description:	epitope description:WDGQRGYKNLFDATLDAL antigen name:Hev b 2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	19185347

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016016
landingPage:	http://www.iedb.org/assay/1657772

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2009

Dimension

study type:	b cell assays
subject species:	Hevea brasiliensis

Person

fullName:	Annick Barre Raphaë l Culerrier Claude Granier Laetitia Selman Willy J Peumans Els J M Van Damme Franç oise Bienvenu Jacques Bienvenu Pierre Rougé

Data Type

method:	western blot

Study

name:	Mapping of IgE-binding epitopes on the major latex allergen Hev b 2 and the cross-reacting 1,3beta-glucanase fruit allergens as a molecular basis for the latex-fruit syndrome.
description:	The epitope was deduced based on IgE reactivity with overlapping 15-mer peptides. Residues within the sequence were predicted to be surface exposed.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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