Identification of type-specific and cross-reactive neutralizing conformational epitopes on the major capsid protein of human papillomavirus type 31.

Title:

Identification of type-specific and cross-reactive neutralizing conformational epitopes on the major capsid protein of human papillomavirus type 31.

Dataset

identifier:	1659116
description:	epitope description:SVPTDLYIK antigen name:Major capsid protein L1 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	16508703

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1015780
landingPage:	http://www.iedb.org/assay/1659116

Publication

type:	Literature
publicationVenue:	Arch Virol
dates:	2006

Dimension

study type:	b cell assays
subject species:	Human papillomavirus type 31

Person

fullName:	M J J Fleury A Touzé E Alvarez G Carpentier C Clavel J-F Vautherot P Coursaget

Data Type

method:	ELISA

Study

name:	Identification of type-specific and cross-reactive neutralizing conformational epitopes on the major capsid protein of human papillomavirus type 31.
description:	The epitope-specific mAb recognized the native and denatured antigen in ELISA. The antigen was composed of intact or denatured L1/L2 proteins. The epitope-specific mAb recognized the wt and two mutated antigen in ELISA. The mutated HPV-16 VLPs contained an insertion of a 6 amino acid HBc sequence within the FG loop, either at postion 266/267 or 283/284.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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