Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein.

Title:

Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein.

Dataset

identifier:	1663051
description:	epitope description:CIEAKLTNTTTESRCPTQGEPSLNEEQDKRFLCKHSMVDRGWGNGCGLFGKGGIVTCAMFTCKKNMEGKVVLPENL antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:4D2
aggregation:	instance of dataset
availability:	available
primaryPublications:	1372140

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000879
landingPage:	http://www.iedb.org/assay/1663051

Publication

type:	Literature
publicationVenue:	Virology
dates:	1992

Dimension

study type:	b cell assays
subject species:	Dengue virus 2

Person

fullName:	F Megret J P Hugnot A Falconar M K Gentry D M Morens J M Murray J J Schlesinger P J Wright P Young M H Van Regenmortel

Data Type

method:	western blot

Study

name:	Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein.
description:	The epitope sequence came from cited reference Deubel et al. Virol 1986 155:365-377. The epitopic region was deduced based on reactivity of the mAb with DENV2 E fragments 1-135 and 60-205.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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