Isolation and characterization of human monoclonal antibodies to digoxin. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Isolation and characterization of human monoclonal antibodies to digoxin.

Dataset

identifier:	1676758
description:	epitope description:digoxin host organism:Mus musculus (CBA/J X C57BL/6J) human IgH Tg human IgL Tg antibody name:7F2-31, 11E6-7, 5C2-4
aggregation:	instance of dataset
availability:	available
primaryPublications:	10438974

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012734
landingPage:	http://www.iedb.org/assay/1676758

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1999

Dimension

study type:	b cell assays
subject species:

Person

fullName:	W J Ball Jr R Kasturi P Dey M S O'Donnell D Hudson D Fishwild

Data Type

method:	antigen inhibition

Study

name:	Isolation and characterization of human monoclonal antibodies to digoxin.
description:	Epitope-specific mAbs 7F2-31, 11E6-7, and 5C2-4 had a 15-, 18-, and 35-fold lower affinity, respectively, for acetylstrophanthidin than for the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.