Substituted ammonium ions as allergenic determinants in drug allergy. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Substituted ammonium ions as allergenic determinants in drug allergy.

Dataset

identifier:	1675053
description:	epitope description:quaternary ammonium ion host organism:Homo sapiens antibody name:Human sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	6196640

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005581
landingPage:	http://www.iedb.org/assay/1675053

Publication

type:	Literature
publicationVenue:	Nature
dates:	1983

Dimension

study type:	b cell assays
subject species:

Person

fullName:	B A Baldo M M Fisher

Data Type

method:	antigen inhibition

Study

name:	Substituted ammonium ions as allergenic determinants in drug allergy.
description:	Serum from a drug-sensitive subject containing alcuronium-reactive IgE antibodies, was inhibited from binding alcuronium-sepharose complexes by heterologous compounds without muscle relaxant activity, but containing ammonium ions. The authors concluded that quaternary and tertiary ammonium ions are the complementary allergic sites on the reactive drugs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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