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Title: Fine specificity of the immune response to oxazolones III. Antibodies but not contact sensitivity specific for 2-furyloxazolone are controlled by an Igh-V gene in the mouse.
identifier: 1676341
description:
epitope description:4-(ethoxymethylene)-2-styryloxazol-5-one
host organism:Mus musculus CBA
aggregation:
instance of dataset
availability:
available
primaryPublications: 6689303
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1012932
landingPage: http://www.iedb.org/assay/1676341
type:
Literature
publicationVenue:
Eur J Immunol
dates:
1983
study type: b cell assays
subject species:
fullName:
O Mä
kelä
A Matoso-Ferreira
M Kaartinen
method:
in vivo skin test
name:
Fine specificity of the immune response to oxazolones III. Antibodies but not contact sensitivity specific for 2-furyloxazolone are controlled by an Igh-V gene in the mouse.
description:
Hypersensitivity was determined by challenging mice with compound and measuring ear weight. Antibody titers were determined by inactivation of T4 phage particles containing styryl Ox-aminocaproyl. Mice immunized with furyl-Ox cross-reacted with Styryl Ox-cap, especially mice with allotype j (strains CBA and C3H). At day 6 the reaction was higher with styryl Ox-cap, but at day 20 it was higher with Furyl Ox-cap.

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