Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1015532 |
| landingPage: |
http://www.iedb.org/assay/1680565 |
| type: |
Literature
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| publicationVenue: |
J Neuroimmunol
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| dates: |
2006
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Michael Khalil
Markus Reindl
Andreas Lutterotti
Bettina Kuenz
Rainer Ehling
Claudia Gneiss
Peter Lackner
Florian Deisenhammer
Thomas Berger
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| method: |
ELISA
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| name: |
Epitope specificity of serum antibodies directed against the extracellular domain of myelin oligodendrocyte glycoprotein: Influence of relapses and immunomodulatory treatments.
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| description: |
No significant difference in reactivity was seen between MS patients and healthy controls. The epitope contained an additional N-terminal SGSG spacer tetrapeptide between the biotin group and the MOG amino acids. No significant changes of immunoreactivities after 1year were observed in patients treated with glatiramer-acetate, in patients treated with interferon-beta, and in patients without any immunomodulatory treatment. The percentage of patients with positive immunoreactivities against the epitope is increased in patients who experienced the last relapse within 1 – 6months before study entry.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
