Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships.

Title:

Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships.

Dataset

identifier:	1677808
description:	epitope description:carbapenem MM22383 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	3338858

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005646
landingPage:	http://www.iedb.org/assay/1677808

Publication

type:	Literature
publicationVenue:	Int Arch Allergy Appl Immunol
dates:	1988

Dimension

study type:	b cell assays
subject species:

Person

fullName:	R G Edwards J M Dewdney R J Dobrzanski D Lee

Data Type

method:	antigen inhibition

Study

name:	Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships.
description:	Serum samples were pre-incubated with the epitope and then the amount of binding to epitope-ovalbumin was monitored. Direct binding was also determined with an RIA. After the patient was no longer exposed to the epitope, the titer declined.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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