Characterization of monoclonal antibodies to Junin virus nucleocapsid protein and application to the diagnosis of hemorrhagic fever caused by South American arenaviruses.

Title:

Characterization of monoclonal antibodies to Junin virus nucleocapsid protein and application to the diagnosis of hemorrhagic fever caused by South American arenaviruses.

Dataset

identifier:	1679572
description:	epitope description:PPSLLFLP antigen name:nucleocapsid protein host organism:Mus musculus BALB/c antibody name:C6-9
aggregation:	instance of dataset
availability:	available
primaryPublications:	19553554

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016578
landingPage:	http://www.iedb.org/assay/1679572

Publication

type:	Literature
publicationVenue:	Clin Vaccine Immunol
dates:	2009

Dimension

study type:	b cell assays
subject species:	Junin mammarenavirus

Person

fullName:	Mina Nakauchi Shuetsu Fukushi Masayuki Saijo Tetsuya Mizutani Agustí n E Ure Victor Romanowski Ichiro Kurane Shigeru Morikawa

Data Type

method:	antigen inhibition

Study

name:	Characterization of monoclonal antibodies to Junin virus nucleocapsid protein and application to the diagnosis of hemorrhagic fever caused by South American arenaviruses.
description:	The epitope was mapped using epitope-blocking ELISA with overlapping synthetic peptides. The epitope was common in several peptides found to block binding of the monoclonal antibody to JUNV NP.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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