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Title: Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice.
identifier: 1680434
description:
epitope description:DEAELPSRISPGKNA
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 10229114
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001184
landingPage: http://www.iedb.org/assay/1680434
type:
Literature
publicationVenue:
J Neuroimmunol
dates:
1999
study type: b cell assays
subject species:
fullName:
F Mokhtarian
Z Zhang
Y Shi
E Gonzales
R A Sobel
method:
ELISA
name:
Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice.
description:
This epitope is an analog of the naturally occurring MOG sequence, DEAELPCRISPGKNA. The aa C was substituted with S in the synthesis at position 7 in the epitope.
The induction of EAE in mice using the epitope generated minimal specific IgG.

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