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identifier: 1683354
description:
epitope description:N-acetyllactosamine
antigen name:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucosylceramide
host organism:Rattus norvegicus BioBreeding
antibody name:E5C2
aggregation:
instance of dataset
availability:
available
primaryPublications: 2432147
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007625
landingPage: http://www.iedb.org/assay/1683354
type:
Literature
publicationVenue:
J Exp Med
dates:
1987
study type: b cell assays
subject species: Rattus norvegicus
fullName:
Y Uchigata
S L Spitalnik
O Tachiwaki
K F Salata
A L Notkins
method:
immuno staining
name:
Pancreatic islet cell surface glycoproteins containing Gal beta 1-4GlcNAc-R identified by a cytotoxic monoclonal autoantibody.
description:
The epitope-specific mAb E5C2 stained the surface of human pancreatic islets after neuraminidase treatment. The authors conclude that the epitope of mAb E5C2 is hidden by sialic acid residues. MAb E5C2 bound to neuraminidase-treated neutral glycolipids from the human leukemia HL-60 cells by RIA.

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