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Title: Phosphorylated and nonphosphorylated epitopes of the La/SSB autoantigen: comparison of their antigenic and conformational characteristics.
identifier: 1690254
description:
epitope description:VTWEVLEGEVEKEALKKI
antigen name:Lupus La protein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 16453388
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007240
landingPage: http://www.iedb.org/assay/1690254
type:
Literature
publicationVenue:
Biopolymers
dates:
2006
study type: b cell assays
subject species: Homo sapiens
fullName:
Nicolas Coudevylle
Dimitrios Rokas
Maria Sakarellos-Daitsiotis
Dimitrios Krikorian
Eugenia Panou-Pomonis
Constantinos Sakarellos
Guy Boussard
Manh Thong Cung
method:
ELISA
name:
Phosphorylated and nonphosphorylated epitopes of the La/SSB autoantigen: comparison of their antigenic and conformational characteristics.
description:
The phosphorylated form of the epitope was better recognized by sera from Sjögren syndrome and SLE sera than its nonphosphorylated counterpart. Conformational analysis showed that the phosphorylated epitope adopts different structural characteristics from those of the corresponding nonphosphorylated epitope.

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