Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1015643 |
| landingPage: |
http://www.iedb.org/assay/1687891 |
| type: |
Literature
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| publicationVenue: |
J Immunol
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| dates: |
2008
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| study type: | b cell assays |
| subject species: | Mus musculus |
| fullName: |
Stefano Scabeni
Marilena Lapilla
Silvia Musio
Barbara Gallo
Emilio Ciusani
Lawrence Steinman
Renato Mantegazza
Rosetta Pedotti
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| method: |
in vivo skin test
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| name: |
CD4+CD25+ regulatory T cells specific for a thymus-expressed antigen prevent the development of anaphylaxis to self.
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| description: |
Mice Immunized with the epitope were resistant to anaphylaxis, as measured by suggestive clinical signs (i.e., reddening of the skin, piloerection, prostration, reduced or lack of response to stimuli) and body temperature. Anti-CD25 Ab treatment reduced the resistance.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
