Chimeric L1-L2 virus-like particles as potential broad-spectrum human papillomavirus vaccines. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Chimeric L1-L2 virus-like particles as potential broad-spectrum human papillomavirus vaccines.

Dataset

identifier:	1690350
description:	epitope description:QLYKTCKQAGTCPPDIIPKV antigen name:Minor capsid protein L2 host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	19640991

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016608
landingPage:	http://www.iedb.org/assay/1690350

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2009

Dimension

study type:	b cell assays
subject species:	Human papillomavirus type 16

Person

fullName:	Christina Schellenbacher Richard Roden Reinhard Kirnbauer

Data Type

method:	biological activity

Study

name:	Chimeric L1-L2 virus-like particles as potential broad-spectrum human papillomavirus vaccines.
description:	The epitope sequence was found in the cited reference, Gambhira et al, J Virol: 81(24) 2007 [PMID: 17928339]. Immunization with the epitope using BPV L1 as the carrier resulted in higher neutralization titers. Using CFA/IFA as adjuvant led to higher titer than using alum as adjuvant.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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