Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus.

Title:

Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus.

Dataset

identifier:	1690926
description:	epitope description:EESDDDMG antigen name:60S acidic ribosomal protein P2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9294205

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003899
landingPage:	http://www.iedb.org/assay/1690926

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	1997

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	D Kaplan I Ferrari P L Bergami E Mahler G Levitus P Chiale J Hoebeke M H Van Regenmortel M J Levin

Data Type

method:	antigen inhibition

Study

name:	Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus.
description:	The epitope partially inhibited the binding of anti-P serum to R13.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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