Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies.

Title:

Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies.

Dataset

identifier:	1690931
description:	epitope description:VAARGRGRGMGRGNI + SCM(R4, R6, R8, R12) antigen name:Small nuclear ribonucleoprotein Sm D3 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15642139

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016150
landingPage:	http://www.iedb.org/assay/1690931

Publication

type:	Literature
publicationVenue:	Arthritis Res Ther
dates:	2005

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Michael Mahler Marvin J Fritzler Martin Blü thner

Data Type

method:	ELISA

Study

name:	Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies.
description:	R4, R6, R8, R12 were symmetrically or asymmetrically dimethylated. The symmetrically dimethylated peptide reacted with the sera. The asymmetrically dimethylated peptide did not react with the sera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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