High affinity cross-reacting mAb generated by minimal mimicry: implications for the pathogenesis of anti-nuclear autoantibodies and immunosuppression.

Title:

High affinity cross-reacting mAb generated by minimal mimicry: implications for the pathogenesis of anti-nuclear autoantibodies and immunosuppression.

Dataset

identifier:	1691024
description:	epitope description:GSFSDADLAD antigen name:CD99 antigen host organism:Mus musculus antibody name:2E1
aggregation:	instance of dataset
availability:	available
primaryPublications:	9520450

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016119
landingPage:	http://www.iedb.org/assay/1691024

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	1998

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	A L Rothermel D C Altieri

Data Type

method:	immunoprecipitation

Study

name:	High affinity cross-reacting mAb generated by minimal mimicry: implications for the pathogenesis of anti-nuclear autoantibodies and immunosuppression.
description:	The epitope-reactive mAb 2E1 immuoprecipitated effector cell protease receptor 1 (EPR-1) from Molt13 T cell extracts. MAb 2E1 immuoprecipitated three proteins, E2, EPR-1, and Ku80, from Molt13 cell extracts and immunoblotted the proteins in extracts from human cells lines HL-60 and U937, human umbilical vein endothelial cells, and activated PBMCs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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