| Title: | Autoimmunity to RNA polymerase II is focused at the carboxyl terminal domain of the large subunit. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1007405 |
| landingPage: |
http://www.iedb.org/assay/1691745 |
| type: |
Literature
|
| publicationVenue: |
Arthritis Rheum
|
| dates: |
1996
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
M Hirakata
J Kanungo
A Suwa
Y
J Craft
J A Hardin
|
| method: |
antigen inhibition
|
| name: |
Autoimmunity to RNA polymerase II is focused at the carboxyl terminal domain of the large subunit.
|
| description: |
The epitope, conjugated to a peptide representing 1.5 heptapeptide repeats of the epitope, but not the free peptide, was able to inhibit immunoprecipitation of Pol II from Hela cell extracts, by the patient sera. The inhibition was complete for 5 sera tested, and partial for 4.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |