Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants.

Title:

Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants.

Dataset

identifier:	1692572
description:	epitope description:NNGNLQLRNKEVTWEVLEG antigen name:Lupus La protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	12428060

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007266
landingPage:	http://www.iedb.org/assay/1692572

Publication

type:	Literature
publicationVenue:	Mol Med
dates:	2002

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	John G Routsias Evgenia Touloupi Eleni Dotsika Avrilia Moulia Vassilios Tsikaris Constantinos Sakarellos Maria Sakarellos-Daitsiotis Haralampos M Moutsopoulos Athanasios G Tzioufas

Data Type

method:	ELISA

Study

name:	Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants.
description:	Fifty-one percent of anti-La positive sera reacted with the epitope. There was no reactivity in anti-La negative sera. The epitope inhibited binding of anti-epitope sera to anti-complementary peptide F(ab')s.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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