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identifier: 1693440
description:
epitope description:alpha-L-Fucp-(1->3)-[alpha-D-Manp-(1->6)-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)]-D-GlcpNAc
antigen name:Acid beta-fructofuranosidase
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 12704374
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1005438
landingPage: http://www.iedb.org/assay/1693440
type:
Literature
publicationVenue:
J Allergy Clin Immunol
dates:
2003
study type: b cell assays
subject species: Solanum lycopersicum
fullName:
Kay Foetisch
Sandra Westphal
Iris Lauer
Mechthild Retzek
Fritz Altmann
Daniel Kolarich
Stephan Scheurer
Stefan Vieths
method:
antigen inhibition
name:
Biological activity of IgE specific for cross-reactive carbohydrate determinants.
description:
The epitope is an N-glycan moiety found in several plant proteins, including the source given and others such as pinneaple bromelain.
From 12 patients with positive recognition of the epitope in a glycopeptide format (linked to 2 to 4 aa as extracted from pineapple bromelain) in ELISA, a pool of 3 sera was tested for inhibition of the recognition of purified natural tomato Lyc e 2 by preincubation with the epitope as a glycopeptide.

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