Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns.

Title:

Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns.

Dataset

identifier:	1693710
description:	epitope description:RSLKMRGQAF antigen name:U1 small nuclear ribonucleoprotein A host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	8621944

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007329
landingPage:	http://www.iedb.org/assay/1693710

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1996

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	J A James J B Harley

Data Type

method:	antigen inhibition

Study

name:	Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns.
description:	This is the minimum epitope that was tested positive. Absorption of patient sera with the epitope significantly inhibited the anti-nRNP protein activity of the sera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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