A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif.

Dataset

identifier:	1693700
description:	epitope description:PAPGMRPP antigen name:U1 small nuclear ribonucleoprotein C host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9802926

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007305
landingPage:	http://www.iedb.org/assay/1693700

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	1998

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	M R Arbuckle A R Schilling J B Harley J A James

Data Type

method:	antigen inhibition

Study

name:	A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif.
description:	Reactivity to the epitope fluctuated between 1990 to 1996. Column depletion of epitope-specific Ab from patient sera severely reduced sera reactivity to the epitope, nRNP A peptide (PPPGMIPP), and Sm B/B' peptides (PPPGMRPP and PPPGMRGP).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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