Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization.

Dataset

identifier:	1695354
description:	epitope description:NGNLQLRNKEVT antigen name:Lupus La protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9158085

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007320
landingPage:	http://www.iedb.org/assay/1695354

Publication

type:	Literature
publicationVenue:	Clin Exp Immunol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	A G Tzioufas E Yiannaki M Sakarellos-Daitsiotis J G Routsias C Sakarellos H M Moutsopoulos

Data Type

method:	antigen inhibition

Study

name:	Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization.
description:	In the presence of the epitope, the binding of patient sera to native La/SSB was reduced in a dose-dependent manner. Sera used was from anti-La/SSB positive individuals with pSS or SLE. The epitope was deduced using overlapping 20-mer spanning the length of La/SSB.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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