Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope.

Dataset

identifier:	1696162
description:	epitope description:PNQEKVSGIPEQEYSC host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	7518436

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007342
landingPage:	http://www.iedb.org/assay/1696162

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	1994

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Y Muro W M Tsai R Houghten E M Tan

Data Type

method:	immuno staining

Study

name:	Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope.
description:	The epitope is a compound peptide of PCNA residues 106-112 and 127-135 with an added C-terminal Cys residue. The epitope-specific rabbit antiserum showed speckled nucleoplasmic staining which was not cell cycle dependent in human HeEp-2 cells by immunofluorescence. The sulfhydryl-modifying reagent thimerosal (TMS) did not affect the nuclear immunofluorescence with the rabbit antiserum.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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