Toward the rational design of a malaria vaccine construct using the MSP3 family as an example: contribution of immunogenicity studies in models.

Title:

Toward the rational design of a malaria vaccine construct using the MSP3 family as an example: contribution of immunogenicity studies in models.

identifier:	1698462
description:	epitope description:PEHKKEENMLSHLYVSSKDKENISKEND antigen name:Merozoite surface protein 3 host organism:Mus musculus C57BL/6
aggregation:	instance of dataset
availability:	available
primaryPublications:	19581391

study type:	b cell assays
subject species:	Plasmodium falciparum 3D7

fullName:	Lena-Juliette Daher Corine G Demanga Eric Prieur Jean-Louis Pé rignon Hasnaa Bouharoun-Tayoun Pierre Druilhe

method:	ELISA

name:	Toward the rational design of a malaria vaccine construct using the MSP3 family as an example: contribution of immunogenicity studies in models.
description:	The 154-249 fragment of MSP3-1 was the most immunogenic fragment tested. Inclusion of aa 254 to 354 reduced immunogenicity. Similar results were observed in BALB/c mice.

name:	iedb
homePage:	http://www.iedb.org

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