DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.

Dataset

identifier:	1699870
description:	epitope description:DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA antigen name:Amyloid beta A4 protein host organism:Mus musculus C57BL/6 x SJL
aggregation:	instance of dataset
availability:	available
primaryPublications:	19861672

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017635
landingPage:	http://www.iedb.org/assay/1699870

Publication

type:	Literature
publicationVenue:	JAMA
dates:	2009

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Doris Lambracht-Washington Bao-Xi Qu Min Fu Todd N Eagar Olaf Stü ve Roger N Rosenberg

Data Type

method:	ELISA

Study

name:	DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.
description:	Immunization with the epitope alone was more effective than immunization with the epitope trimer encoding DNA. Sera from peptide immunized animals responded to the peptide, sera from DNA immunized animals did not.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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