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Title: Functional epitope analysis of the second extracellular loop of the human heart muscarinic acetylcholine receptor.
identifier: 1699988
description:
epitope description:VEDGECYIQF
antigen name:Muscarinic acetylcholine receptor M2
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 7539085
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011173
landingPage: http://www.iedb.org/assay/1699988
type:
Literature
publicationVenue:
J Mol Cell Cardiol
dates:
1995
study type: b cell assays
subject species: Rattus norvegicus
fullName:
M L Fu
W Schulze
G Wallukat
A Hjalmarson
J Hoebeke
method:
biological activity
name:
Functional epitope analysis of the second extracellular loop of the human heart muscarinic acetylcholine receptor.
description:
The epitope specific antibody inhibited beating of spontaneously beating neonatal rat cardiomyocytes by binding to the M2 muscarinic receptor. The epitope specific antibody did not inhibit binding of QNB agonist to the M2 muscarinic receptor on rat mycardial membranes. Binding of the epitope specific sera to rat M2 muscarinic receptor was also measured by immunohistochemistry.

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