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Title: Vaccination with a MHC class II peptide attenuates cellular and humoral responses against tAChR and suppresses clinical EAMG.
identifier: 1700173
description:
epitope description:NSQPEILERTRAELD
antigen name:H-2 class II histocompatibility antigen, A beta chain
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 12389643
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016896
landingPage: http://www.iedb.org/assay/1700173
type:
Literature
publicationVenue:
Autoimmunity
dates:
2002
study type: b cell assays
subject species: Mus musculus
fullName:
Minako Oshima
Philip Deitiker
Tetsuo Ashizawa
M Zouhair Atassi
method:
in vivo assay
name:
Vaccination with a MHC class II peptide attenuates cellular and humoral responses against tAChR and suppresses clinical EAMG.
description:
IgM and IgG were measured together. Epitope treatment before tAChR induction of experimental autoimmune myasthenia gravis induced tolerance in mice as demonstrated by reduction of Ab response to the tAChR protein.

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