Suppression of experimental myasthenia gravis by monoclonal antibodies against MHC peptide region involved in presentation of a pathogenic T-cell epitope.

Title:

Suppression of experimental myasthenia gravis by monoclonal antibodies against MHC peptide region involved in presentation of a pathogenic T-cell epitope.

Dataset

identifier:	1700242
description:	epitope description:NSQPEILERTRAELD antigen name:H-2 class II histocompatibility antigen, A beta chain host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	10742555

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016908
landingPage:	http://www.iedb.org/assay/1700242

Publication

type:	Literature
publicationVenue:	J Neuroimmunol
dates:	2000

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	N Nakayashiki M Oshima P R Deitiker T Ashizawa M Z Atassi

Data Type

method:	in vivo assay

Study

name:	Suppression of experimental myasthenia gravis by monoclonal antibodies against MHC peptide region involved in presentation of a pathogenic T-cell epitope.
description:	Induction of tolerance by adoptive transfer of epitope-specific mAb was demonstrated by loss of T cell proliferation responses.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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