Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1700415 |
| description: |
epitope description:E56, G68, E70, R101, G102, S103, K104, P105, D107
antigen name:T-cell surface glycoprotein CD3 epsilon chain
host organism:Mus musculus BALB/c
antibody name:OKT3
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
15136729 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/310 |
| landingPage: |
http://www.iedb.org/assay/1700415 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2004
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Lars Kjer-Nielsen
Michelle A Dunstone
Lyudmila Kostenko
Lauren K Ely
Travis Beddoe
Nicole A Mifsud
Anthony W Purcell
Andrew G Brooks
James McCluskey
Jamie Rossjohn
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.
|
| description: |
The affinity of the epitope-specific Fab in complex with a single chain construct of gamma and epsilon chains of the CD3 molecule was determined by SPR. The measurement at equilibrium was 2.63 µM, while the calculated affinity from the kinetic constants was 2.73 µM.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
