Monoclonal antibodies to the main immunogenic region of the nicotinic acetylcholine receptor bind to residues 61-76 of the alpha subunit.

Title:

Monoclonal antibodies to the main immunogenic region of the nicotinic acetylcholine receptor bind to residues 61-76 of the alpha subunit.

identifier:	1700610
description:	epitope description:VDYNLKWNPDDYGGVK antigen name:Acetylcholine receptor subunit alpha host organism:Rattus norvegicus Lewis antibody name:6
aggregation:	instance of dataset
availability:	available
primaryPublications:	2451673

study type:	b cell assays
subject species:	Mus musculus

fullName:	J M Gabriel A Mauron G J Hughes B Roth C Alliod S J Tzartos M Ballivet

method:	western blot

name:	Monoclonal antibodies to the main immunogenic region of the nicotinic acetylcholine receptor bind to residues 61-76 of the alpha subunit.
description:	The epitope sequence is identical in human and calf acetylcholine receptor alpha subunit. The epitope specific mAb reacted with constructs containing fragments of chicken nicotinic AChR, which contains a sequence (TDINLKWNPDDYGGVK) that differs from the epitope at two residues.

name:	iedb
homePage:	http://www.iedb.org

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