Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.

Dataset

identifier:	1700935
description:	epitope description:SHLVEALYLVCGERG antigen name:Insulin, isoform 2 host organism:Mus musculus B16:A dKO NOD
aggregation:	instance of dataset
availability:	available
primaryPublications:	17607359

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007430
landingPage:	http://www.iedb.org/assay/1700935

Publication

type:	Literature
publicationVenue:	J Clin Invest
dates:	2007

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Maki Nakayama Joshua N Beilke Jean M Jasinski Masakazu Kobayashi Dongmei Miao Marcella Li Marilyne G Coulombe Edwin Liu John F Elliott Ronald G Gill George S Eisenbarth

Data Type

method:	radio immuno assay (RIA)

Study

name:	Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.
description:	All B16:A-dKO mice (15 of 15) immunized with the B16:A insulin B:9–23 peptide similarly produced insulin autoantibodies (IAAs) that were absorbed by human insulin. B16:Y NOD mice immunized with B16:Y insulin B:9–23 peptide also produced IAAs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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